NEURILEMMOMA (SCHWANNOMA) DEFINATION
Neurilemmoma are benign neoplasms derived from the Schwann cells. These cells are neuro-ectodermal in origin and they envelope the axons of the peripheral nerves in the form of a membrane.
NEURILEMMOMA (SCHWANNOMA) CLINICAL FEATURE:
Age: The lesion usually arises before the age of 45years.
Sex: Females are affected more often than males.
Site: Neurilemmoma can occur in relation to both the intracranial and the peripheral nerves.
NEURILEMMOMA (SCHWANNOMA) PRESENTATION:
- Neurilemmoma clinically presents a slow enlarging, well-circumscribed, painless, nodule of varying size.
- The lesion is smooth, firm, exophytic and often appears as a movable swelling beneath the mucosa, which may be tendered to palpation.
- Some lesions may grow at a faster pace with pain and paresthesia
NEURILEMMOMA (SCHWANNOMA) RADIOGRAPHIC FEATURE:
Radiographically central Neurilemmoma present well-defined, unilocular or multilocular radiolucent areas in the jawbone, with expansion and distortion of the cortical palates.
NEURILEMMOMA (SCHWANNOMA) HISTOPATHOLOGY:
- The neoplasm is well demarcated from the surrounding normal tissue by a true capsule or a pseudo capsule of fibrous connective tissue.
- The basic cellular constituents of the lesion are the proliferating spindle-shaped, neoplastic Schwann cells, having elongated nuclei
- These cells are arranged in two distinct patterns which are pathognomonic for the Neurilemmoma
NEURILEMMOMA (SCHWANNOMA) DIFFERENTIAL DIAGNOSIS:
- Fibro epithelial polyp
- Peripheral giant cell granuloma
NEURILEMMOMA (SCHWANNOMA) TREATMENT: