Molecular structure

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molecular structure











In order to design a proper and effective steroid cycle, Medifit Education suggest that one should have proper understanding of chemical nature of Testosterone and Anabolic steroids.

Anabolic steroids used for muscle building or for medical uses are having androgenic and anabolic properties, whose chemical structures only, are given by Medifit Education.

Androgens exert some kind of masculinizing physical effect on the body, while anabolics promote growth. However, these distinctions are not completely exclusive. For example, testosterone is synthesized by the adrenal cortex as well as the testes, and has both anabolic and androgenic properties.

Steroids are fat-soluble hormones with a tetracyclic base structure. The base structure consists of four fused rings: three cyclohexane rings and one cyclopentane. The basic structural backbone can be seen below:

molecular structure 2.png




As you can see, each of the rings is designated by a letter. Rings A and D are the most commonly modified rings. The following diagram shows the numbering of the carbons in steroids, which will be useful later in this article. The two methyl groups on C10 and C13 are also designated with numbers, as they are present in most steroids.

molecular structure 3




Steroids are synthesized in the body from squalene, a complex linear aromatic molecule shown below:


molecular structure 4

Squalene is cyclized to form cholesterol. In the first few steps of this chemical pathway, squalene is converted tosqualene epoxide, which has a different double-bond bond distribution that is necessary for the ring fusion to occur. In ten complex steps of cyclization and carbocation, squalene epoxide is converted to Lanosterol. This reaction is catalyzed by the enzyme cyclase. The lanosterol is then downgraded, with three methyl groups being removed, and cholesterol is formed. This process of the cyclization of squalene is considered to be one of the most fascinating and complex reactions in organic chemistry.







By Medifit Education

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