Ambroxol

You are here: Home / Ambroxol

 

 

 

 

 

By Medifit Education

 

Ambroxol

syrup

 

1.       TYPE OF DRUG-Ambroxol
Ambroxol is a clinically proven systemically active mucolytic agent.

 

2.       INDICATIONS (USE)-Ambroxol
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain.

 

3.       MECHANISM OF ACTION (MOA)-Ambroxol
Ambroxol is a metabolite of bromhexine and is used similarly as a mucolytic.

 

4.       ROUTES OF ADMINISTRATION-Ambroxol
tablets & Syrup

 

5.       ONSET OF EFFECT OR ACTION-Ambroxol
Oral : after about 30 minutes.

 

6.     DOSAGE (DOSING INFORMATION)-Ambroxol
Adults: daily dose of 30 mg (one Ambroxol tablet ) to 120 mg (4 Ambroxol tablets) taken in 2 to 3 divided doses

Children up to 2 years: half a teaspoonful Ambroxol syrup twice daily

Children 2 – 5 years: half a teaspoonful Ambroxol syrup 3 times daily

Children over 5 years: One teaspoonful Ambroxol syrup 2-3 times daily

 

7.       HALF LIFE (DURATION OF ACTION)-Ambroxol
1.3 hours.

 

8.       ADVERSE EFFECTS OR SIDE EFFECTS-Ambroxol
Occasional gastrointestinal side effects may occur but these are normally mild.

 

9.       CONTRAINDICATIONS-Ambroxol
There are no absolute contraindications but in patients with gastric ulceration relative caution should be observed.

 

10.   DRUG INTERACTIONS-Ambroxol
When concurrently used with antibiotics i.e. amoxicilline, cefuroxime, erythromycin, doxycyclineleads to higher antibiotic concentration in the lung issue.

 

11.     EXCRETION-Ambroxol
The drug is metabolized in the liver by conjugation with the formation of pharmacologically inactive metabolites. About 90% of ambroxol excreted in the urine: 90% of them in the form of metabolites and 10% unchanged.

 

 

Ambroxol 1

By Medifit Education

www.themedifit.in