245. Nature & Nurture In Psychiatry

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245. Nature & Nurture In Psychiatry

245. Nature & Nurture In Psychiatry

CATEGORY: Medical & Medicine – 500 Courses

COURSE NUMBER: 245

FEES: 555/- INR only

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Syllabus

List of contributors vii
Foreword by James D Watson xiii
Preface xv
SECTION I. The study of gene–environment interplay
1. The most stupendous era in the history of psychiatry? 1
Peter McGuffin and Sarah Cohen
2. Types of gene–environment interplay and their statistical properties 11
Pak C Sham
3. The myth of the heritability index 19
Sharon Schwartz and Ezra Susser
SECTION II. Cognitive ability and disability through the lifespan
4. Do heavier babies make brighter children? 27
Marcus Richards
5. Gene–environment interactions and correlations in the 35
development of cognitive abilities and disabilities
Robert Plomin and Oliver Palfrey-Davis
6. Cognitive function and impairment in elderly twins 47
Nancy L Pedersen
SECTION III. Childhood and development
7. Genetic regulation of complex social behaviour in a monogamous rodent 57
Heather E Ross and Larry J Young
8. Childhood adversity, monoamine oxidase A genotype and
risk for conduct disorder 67
Brien Riley
9. Genetics and environment in ADHD 79
Anita Thapar

SECTION IV. Affective disorders
10. Genetics of bipolar disorder 87
Nick Craddock and Elen Russell
11. Stressful life events, 5-HTT genotype and risk of depression 95
Stanley Zammit and Michael J Owen
12. Genetic variation in 5-HT signalling, amygdala reactivity and 103
susceptibility for affective disorders
Ahmad R Hariri
13. Adolescent depression: is cortisol vulnerability genetic? 111
Ian M Goodyer
SECTION V. Psychosis: Now that we have some genes
14. Genes for schizophrenia and beyond 119
Hywel J Williams, Nadine Norton, Michael C O’Donovan
and Michael J Owen
15. Genes, hypoxia and schizophrenia 127
Tyrone D Cannon
16. Genes, cannabis and psychosis 141
Mary Cannon, Michelle Harley, Mary Catherine Clarke
and Louise Arseneault
SECTION VI. Addictions
17. Genetic epidemiology of alcohol dependence:
the Collaborative study On the Genetics of Alcoholism 157
John P Rice
18. Imaging vulnerability factors in addiction with PET and [11C]raclopride 167
Isabelle Boileau, Chawki Benkelfat, Marco Leyton, Mirko Diksic
and Alain Dagher
SECTION VII. Did God forget to read DSM-IV?
19. Did God forget to read DSM? Genes are not diagnosis-specific 177
Marcella Rietschel
20. Are the genetic and environmental factors impacting on
schizophrenia and bipolar disorder the same or different? 185
Robin M Murray, Paul Fearon, Mary Cannon, Colm McDonald,
Jolanta Zanelli and Alastair Cardno
21. Genotype–environment interaction – sometimes there, sometimes not 193
Kenneth S Kendler
Index 215

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