110. Structure & Mechanism In Protein Science

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110. Structure & Mechanism In Protein Science

 

 

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COURSE NUMBER: 110

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Syllabus

Contributors vii
Preface xi
Introduction to the Wiley Series in Protein
and Peptide Science xiii
1 Fundamentals of Protein Folding 1
Vladimir N. Uversky
2 Recruiting Unfolding Chaperones to Solubilize Misfolded
Recombinant Proteins 63
Rayees U.H. Mattoo and Pierre Goloubinoff
3 Osmolytes as Chemical Chaperones to Use in Protein
Biotechnology 77
Ario de Marco
4 Inclusion Bodies in the Study of Amyloid Aggregation 93
Anna Villar-Piqué and Salvador Ventura
5 Protein Aggregation in Unicellular Eukaryotes 117
Marina Caldara, Joris Winderickx, and Vanessa Franssens
6 Structural Properties of Bacterial Inclusion Bodies 151
Antonino Natalello, Diletta Ami, and Silvia Maria Doglia

7 Residue-Specific Structural Studies of Inclusion Bodies 181
Christian Wasmer, Marielle Wälti, Yongli Chen, and Lei Wang
8 Biomedical Applications of Bacterial Inclusion Bodies 203
Imma Ratera, Spela Peternel, Joaquin Seras-Franzoso,
Olivia Cano-Garrido, Elena García-Fruitós, Rafael Cubarsí,
Esther Vazquez, José Luis Corchero, Escarlata Rodríguez-Carmona,
Jaume Veciana, and Antonio Villaverde
9 Aggregation of Recombinant Proteins: Understanding
Basic Issues to Overcome Production Bottlenecks 221
Marina Lotti and Loredano Pollegioni
10 Fusion to a Pull-Down Module: Designing Enzymes to
Form Biocatalytically Active Insoluble Aggregates 247
Bernd Nidetzky
Index 263

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