101. Herbal Medicines For Fatty Liver Diseases

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101. Herbal Medicines For Fatty Liver Diseases

 

 

CATEGORY:Alternative Medicines 300 Courses

COURSE NUMBER: 101

FEES: 555/- INR only

CERTIFICATE VALIDITY: Lifetime

CERTIFICATES DELIVERY: In 48 hours

BOOKS/ MANUALS: Pages

Syllabus

HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
PLAIN LANGUAGE SUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
BACKGROUND . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Figure 1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Figure 2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Figure 3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Figure 4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
AUTHORS’ CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
CHARACTERISTICS OF STUDIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
DATA AND ANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
Analysis 1.1. Comparison 1 Medicinal herbs versus placebo, Outcome 1 ALT (U/L). . . . . . . . . . . . 158
Analysis 1.2. Comparison 1 Medicinal herbs versus placebo, Outcome 2 AST (U/L). . . . . . . . . . . . 159
Analysis 1.3. Comparison 1 Medicinal herbs versus placebo, Outcome 3 Liver/spleen CT ratio. . . . . . . . . 159
Analysis 2.1. Comparison 2 Herbal medicines plus lifestyle intervention versus placebo plus lifestyle intervention, Outcome
1 AST (U/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160
Analysis 2.2. Comparison 2 Herbal medicines plus lifestyle intervention versus placebo plus lifestyle intervention, Outcome
2 ALT (U/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160
Analysis 2.3. Comparison 2 Herbal medicines plus lifestyle intervention versus placebo plus lifestyle intervention, Outcome
3 ALP (U/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161
Analysis 2.4. Comparison 2 Herbal medicines plus lifestyle intervention versus placebo plus lifestyle intervention, Outcome
4 Liver/spleen CT ratio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161
Analysis 3.1. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 1 ALT
(IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162
Analysis 3.2. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 2 AST
(IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163
Analysis 3.3. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 3
Ultrasound: liver score. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163
Analysis 3.4. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 4 Liver CT
without improvement. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164
Analysis 3.5. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 5 Adverse
events. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 164
Analysis 3.6. Comparison 3 Herbal medicines plus lifestyle intervention versus lifestyle intervention, Outcome 6 GGT
(U/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165
Analysis 4.1. Comparison 4 Herbal medicines versus conventional therapy, Outcome 1 ALT (IU/L). . . . . . . 165
Analysis 4.2. Comparison 4 Herbal medicines versus conventional therapy, Outcome 2 AST (IU/L). . . . . . . 167
Analysis 4.3. Comparison 4 Herbal medicines versus conventional therapy, Outcome 3 GGT (U/L). . . . . . . 168
Analysis 4.4. Comparison 4 Herbal medicines versus conventional therapy, Outcome 4 ALP (U/L). . . . . . . 169
Analysis 4.5. Comparison 4 Herbal medicines versus conventional therapy, Outcome 5 Abnormal ultrasound. . . . 170
Analysis 4.6. Comparison 4 Herbal medicines versus conventional therapy, Outcome 6 Abnormal AST (> 50 U/L). . 170
Analysis 4.7. Comparison 4 Herbal medicines versus conventional therapy, Outcome 7 Abnormal ALT (> 50 U/L). . 171
Analysis 4.8. Comparison 4 Herbal medicines versus conventional therapy, Outcome 8 Adverse events. . . . . . 172
Analysis 5.1. Comparison 5 Herbal medicines plus conventional therapy versus conventional therapy, Outcome 1 ALT
(IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172


Analysis 5.2. Comparison 5 Herbal medicines plus conventional therapy versus conventional therapy, Outcome 2 AST
(IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
Analysis 5.3. Comparison 5 Herbal medicines plus conventional therapy versus conventional therapy, Outcome 3 GGT
(IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
Analysis 5.4. Comparison 5 Herbal medicines plus conventional therapy versus conventional therapy, Outcome 4 Hepatic
ultrasound without improvement. . . . . . . . . . . . . . . . . . . . . . . . . . . . 174
Analysis 6.1. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 1 ALT (IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . 175
Analysis 6.2. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 2 AST (IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . 177
Analysis 6.3. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 3 GGT (IU/L). . . . . . . . . . . . . . . . . . . . . . . . . . 182
Analysis 6.4. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 4 L/S CT ratio. . . . . . . . . . . . . . . . . . . . . . . . . . 185
Analysis 6.5. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 5 Ultrasound without improvement. . . . . . . . . . . . . . . . . . . 186
Analysis 6.6. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 6 Ultrasound: proximal diffuse high echogenic dots. . . . . . . . . . . . . 187
Analysis 6.7. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 7 Ultrasound: distal end echo attenuation. . . . . . . . . . . . . . . . . 187
Analysis 6.8. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 8 Ultrasound: unclear hepatic vessel structure. . . . . . . . . . . . . . . 188
Analysis 6.9. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 9 Ultrasound: reduction of blood flow. . . . . . . . . . . . . . . . . . 188
Analysis 6.10. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 10 Liver CT without improvement. . . . . . . . . . . . . . . . . . . 189
Analysis 6.11. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 11 Adverse events. . . . . . . . . . . . . . . . . . . . . . . . . 189
Analysis 6.12. Comparison 6 Herbal medicines plus lifestyle intervention versus conventional therapy plus lifestyle
intervention, Outcome 12 Ultrasound: liver score. . . . . . . . . . . . . . . . . . . . . . 190
Analysis 7.1. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 1 Liver/spleen CT ratio. . . . . . . . . . . . . . 190
Analysis 7.2. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 2 ALT (U/L). . . . . . . . . . . . . . . . . 191
Analysis 7.3. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 3 AST (U/L). . . . . . . . . . . . . . . . . 192
Analysis 7.4. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 4 GGT (U/L). . . . . . . . . . . . . . . . . 193
Analysis 7.5. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 5 Ultrasound: liver echo intensity. . . . . . . . . . 194
Analysis 7.6. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 6 Abnormal ultrasound. . . . . . . . . . . . . . 195
Analysis 7.7. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 7 Liver CT value. . . . . . . . . . . . . . . . 195
Analysis 7.8. Comparison 7 Herbal medicines plus lifestyle intervention plus conventional therapy versus lifestyle
intervention plus conventional therapy, Outcome 8 Adverse events. . . . . . . . . . . . . . . . 196
ADDITIONAL TABLES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196
APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242
CONTRIBUTIONS OF AUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
DECLARATIONS OF INTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
SOURCES OF SUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
DIFFERENCES BETWEEN PROTOCOL AND REVIEW . . . . . . . . . . . . . . . . . . . . . 249
INDEX TERMS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249

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